The Proof of Immune Harm Is In The Pudding

As obvious as gravity

We don’t need to know how gravity works to acknowledge it exists.

T Cell falling into black hole: Grok

Nevertheless, we know how covid harms the immune system to the extent to have predicted the immune harm, to the surprise of everyone who believed it was like the common cold or influenza. I’d like to draw your attention to a denialist here:

Marc uses gish gallop in order to obfuscate the immune harm from covid

1) The phenotypes from infection, broad activation and high differentiation status show there is nonspecific T cell activation. This paper shows T cell exhaustion from sars cov 2 to other pathogens https://insight.jci.org/articles/view/146701…

2) There are papers showing primed T cell apoptosis from sars cov 2, and the infection of T cells by sars cov 2 https://nature.com/articles/s41418-022-00936-x… The cd8 response is dulled after infection https://nih.gov/news-events/news-releases/sars-cov-2-infection-weakens-immune-cell-response-vaccination…

3) Mechanism includes infection of T cells and broad activation 4) Epidemiologic evidence is a lagging marker, and a basic scientist would more likely been able to project this, like I had. Nevertheless, bad advice from scientists like Marc facilitated and even encouraged infection and antigenic immune escape, so now we can see the immune response to other pathogens is harmed. https://thelancet.com/journals/laninf/article/PIIS1473-3099(24)00831-4/abstract?dgcid=raven_jbs_aip_email…

People who had covid were more likely to be infected with other pathogens subsequently. The T cell damage was evident from the broad activation and differentiation. The problem is, he can claim that those people had exhaustion without Covid being the cause and that they were predisposed to getting Covid because of a pre-existing exhaustion. This is like the people that ask for experiments where HIV was introduced and then subsequently they get AIDS.

Essentially he is just a denialist. He’s also asking for the mechanism, which is not necessary to prove that Covid actually has the effect. Many people research the mechanism behind gravity, we don’t need to prove how it works in order to prove gravity exists. People are still even arguing over the mechanism of HIV’s harm to CD4 T cells but because they actually don’t know and it’s not 100% certain that it’s simply from dividing in the T cell. It could also be from chronically activating it with a superantigen.

Finally, asking for infection controls is code for asking for studies in which people were intentionally infected rather than matched because he’s trying to claim there is confounding. The recent study that was published in the Lancet shows an increase in risk for other infections and for hospitalization by those other infections after Covid. When you ask this guy who argued that people should count on this being like any other cold, he’s going to be the second to last to admit that harms the immune system.

Take care,

AJ